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Filtered Search Results
Medchemexpress LLC Way-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g/mol | C29H38N4O6 | 10 MG
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WAY-100635 maleate is the maleate salt of WAY-100635, a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist supplied for research use in in vitro and in vivo pharmacology studies.
- Potent 5-HT1A receptor antagonist (IC50 0.91 nM; Ki 0.39 nM)
- High purity (≈99.6%) suitable for analytical and pharmacological studies
- Molecular weight 538.64 g/mol; formula C29H38N4O6
- Available in small pack sizes for research, including 10 mg
- For research use only; not for human or veterinary use
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Medchemexpress LLC Filgotinib (maleate) | 1802998-75-9 | 99.88% | 541.58 | 100 MG
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Filgotinib maleate is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. It inhibits the activities of JAK1, JAK2, JAK3, and TYK2. It also inhibits HIV-1 driven gene transcription and reduces the proliferation of HIV-1 infected cells. It is used in the study of rheumatoid arthritis and inflammatory bowel disease.
- Selectively inhibits JAK1 with high potency
- Demonstrates anti-inflammatory and antiviral properties
- Inhibits Th2 and Th1 cell differentiation in a dose-dependent manner
- Produces dose-dependent bone damage protection in rat models of collagen-induced arthritis
- Reduces inflammatory cell infiltration and protects articular cartilage and bone
- Reduces serum levels of inflammatory cytokines and chemokines
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Medchemexpress LLC Ro 25-6981 Maleate | 1312991-76-6 | 99.25% | 455.54 | 100 MG
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Ro 25-6981 Maleate is a potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist. It demonstrates anticonvulsant and anti-parkinsonian activity and has potential for research into Parkinson's disease.
- Potent, selective, and activity-dependent NR2B subunit-specific NMDA receptor antagonist
- Demonstrates anticonvulsant activity
- Demonstrates anti-parkinsonian activity
- Potential for Parkinson's disease research
- Induces contraversive rotations in 6-OHDA-lesioned rats
- Exhibits age- and activation-dependent anticonvulsant action
- Shows analgesic effects on incision pain in rats
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Medchemexpress LLC Trimebutine (maleate) | 34140-59-5 | 99.66% | 5 G
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Trimebutine (maleate) | 34140-59-5 | 99.66% | 5 G
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Medchemexpress LLC Indacaterol maleate | 753498-25-8 | 99.6% | C28H32N2O7 | 50 MG
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Indacaterol maleate (Standard) is the analytical standard of Indacaterol maleate and is intended for research and analytical applications. It is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist that inhibits NF-κB activity in a β-arrestin2-dependent manner. This helps in preventing further lung damage and improving lung function in COPD.
- Can be used in cardiovascular disease research.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Helps in preventing further lung damage and improving lung function in COPD.
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eMolecules Methyl 4-fluorocinnamate | 96426-60-7 | MFCD00297011 | 25g
Oakwood Chemical | Methyl 4-fluorocinnamate | 25g | 537706891 | 098862 | | 96426-60-7 | MFCD00297011 | 180.178 | C10H9FO2
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Cayman Chemical Thioperamide maleate
A selective histamine H3 receptor antagonist that crosses the blood-brain barrier; binds to rat cerebral cortical cells in vitro with a pKi value of 8.4
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Apexbio Technology LLC Flupirtine maleate 75507-68-5 1g
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Flupirtine maleate (CAS 75507-68-5) is a non-opioid analgesic compound characterized by its modulatory effects on neuronal excitability It acts primarily by opening neuronal potassium channels leading to membrane stabilization and reduced excitatory neurotransmission Additionally flupirtine exerts indirect antagonism of N-methyl-D-aspartate (NMDA) receptors which contributes to its analgesic and muscle relaxant effects Due to this dual mechanism flupirtine maleate is utilized in research focusing on pain modulation neuroprotection and the investigation of NMDA receptor-mediated pathways
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Medchemexpress LLC Tegaserod maleate | 189188-57-6 | 99.9% | C20H27N5O5 | 50 MG
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Tegaserod maleate is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. This compound induces tumor cell apoptosis, attenuates PI3K/Akt/mTOR signaling, and reduces S6 phosphorylation. It demonstrates anti-tumor activity and is being investigated for its potential in irritable bowel syndrome (IBS) research.
- Orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist
- 5-HT2B receptor antagonist
- Induces tumor cell apoptosis
- Attenuates PI3K/Akt/mTOR signaling
- Reduces S6 phosphorylation
- Demonstrates anti-tumor activity
- Potential for irritable bowel syndrome (IBS) research
- For research use only
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Apexbio Technology LLC Trimipramine (maleate) 521-78-8 1g
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Trimipramine (maleate) is a tricyclic antidepressant that exerts antagonistic activities at histamine H1 serotonin 5-HT2A and 1-adrenergic receptors with reported Kd values of 0 27 nM 24 nM and 24 nM respectively It also moderately interacts with muscarinic cholinergic receptors (Kd 58 nM) and dopamine D2 receptors (Kd 180 nM) Additionally trimipramine exhibits modest inhibitory effects on serotonin reuptake (Ki 149 nM for SERT) with weaker inhibition of norepinephrine (Ki 2 5 M for NET) and dopamine transporters (Ki 3 8 M for DAT) It is frequently utilized in neuropharmacological research to explore receptor-mediated neuronal signaling pathways and therapeutic mechanisms underlying depression
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![eMolecules Ambeed / Ethyl 444-trifluorocrotonate / 1g / 575774927 / A738483 / / 406-10-0 / [null] / 168.115 / C6H7F3O2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502420125.JPG-250.jpg)
eMolecules Ambeed / Ethyl 444-trifluorocrotonate / 1g / 575774927 / A738483 / / 406-10-0 / [null] / 168.115 / C6H7F3O2
Ambeed / Ethyl 444-trifluorocrotonate / 1g / 575774927 / A738483 / / 406-10-0 / [null] / 168.115 / C6H7F3O2
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Apexbio Technology LLC L-693,403 maleate 207455-21-8 50mg
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L-693 403 maleate (CAS 207455-21-8) is a small molecule exhibiting high affinity and selectivity for sigma ( ) receptors By modulating receptor-mediated signaling pathways it influences neuronal signal transduction at the molecular level Preclinical studies indicate that L-693 403 maleate possesses analgesic properties likely through its regulatory effects on neural activity Owing to these pharmacological characteristics it is utilized in exploratory research on neurological disorders supporting its value as a tool compound in the investigation of neural modulation mechanisms
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Electron Microscopy Sciences HMPA (2-Hydroxypropyl Methacrylate) 450 ML
(Propylene glycol monomethacrylate)
C₇H₁₂O₃ F.W. 144.17
Solubility: 13%
Boiling point: 70°C/1mmHg
Methacrylate is a water miscible monomer. Inhibited with approx. 300ppm MEHQ.
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Ambeed tertButyl propiolate
tert-Butyl propiolate, 13831-03-3, 95%
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eMolecules AstaTech / FORMIC ACID HYDRAZIDE / 25g / 385237248 / F11944 / 95.000 / 624-84-0 / MFCD00007589 / 60.056 / CH4N2O
AstaTech / FORMIC ACID HYDRAZIDE / 25g / 385237248 / F11944 / 95.000 / 624-84-0 / MFCD00007589 / 60.056 / CH4N2O
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